Tyrphostin AG 528

CAS No. 133550-49-9

Tyrphostin AG 528 ( Tyrphostin AG-528; Tyrphostin-B66 )

Catalog No. M17953 CAS No. 133550-49-9

Tyrphostin AG 528 is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 39 In Stock
10MG 55 In Stock
25MG 120 In Stock
50MG 219 In Stock
100MG 393 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tyrphostin AG 528
  • Note
    Research use only, not for human use.
  • Brief Description
    Tyrphostin AG 528 is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).
  • Description
    Tyrphostin AG-528, also known as Tyrphostin B66, is a EGFR protein tyrosine kinase inhibitor.
  • Synonyms
    Tyrphostin AG-528; Tyrphostin-B66
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    EGFR;ErbB2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    133550-49-9
  • Formula Weight
    306.32
  • Molecular Formula
    C18H14N2O3
  • Purity
    98%
  • Solubility
    DMSO : 25 mg/mL 81.61 mM;
  • SMILES
    C1CN(C2=CC=CC=C21)C(=O)/C(=C/C3=CC(=C(C=C3)O)O)/C#N
  • Chemical Name
    N-(3′,4′-Dihydroxybenzylidenecyanoacetyl)indoline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Naijue Zhu, et al. Tyrphostin Tumor Growth Inhibitors of EGFR and ErbB2 Tyrosine Kinase. J Chem Crystallogr. 2007, 37, 679–683.
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